5 posts
A decade-by-decade view of which blood measurements carry information, how often to repeat them, and why interpretation gets harder after 70. Written for people who want to keep their own longitudinal record.
A plain answer to what genetic screening is, how it differs from diagnostic testing, and how to analyze a whole-genome VCF yourself: gene lists, callers, annotation, coverage failure modes, and when you need a clinician.
What whole-genome screening in a healthy adult finds, what it misses, which files and tools to use, and where the interpretation gets hard enough that you need a clinician.
A technical account of what blood-based cancer detection measures, where the numbers come from, and how to read cfDNA methylation tests, tumor markers, and routine CBC results without fooling yourself.
A technical read on GRAIL's methylation-based multi-cancer early detection test: the assay, sensitivity by stage, and why the NHS trial result matters.